Intravenous AAV9 Efficiently Transduces Myenteric Neurons in Neonate and Juvenile Mice
Our recent discovery that adeno-associated virus type 9 (AAV9) can cross the blood brain barrier holds promise for the treatment of global neurological disease. Early studies with AAV9 gene therapy focused on transduction within the brain and spinal cord, but intravenous infusion results in widespr...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-10-01
|
| Series: | Frontiers in Molecular Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00081/full |