Remodeling of Intracellular Ca<sup>2+</sup> Homeostasis in Rat Hippocampal Neurons Aged In Vitro

Remodeling of Intracellular Ca<sup>2+</sup> Homeostasis in Rat Hippocampal Neurons Aged In Vitro

Aging is often associated with a cognitive decline and a susceptibility to neuronal damage. It is also the most important risk factor for neurodegenerative disorders, particularly Alzheimer&#8217;s disease (AD). AD is related to an excess of neurotoxic oligomers of amyloid &#946; peptide (A&...

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Bibliographic Details
Main Authors: Maria Calvo-Rodriguez, Elena Hernando-Pérez, Sara López-Vázquez, Javier Núñez, Carlos Villalobos, Lucía Núñez
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
calcium
hippocampal neurons
aging
alzheimer’s disease
amyloid beta oligomers
endoplasmic reticulum
mitochondria
Online Access:https://www.mdpi.com/1422-0067/21/4/1549

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https://www.mdpi.com/1422-0067/21/4/1549

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