INH Direnç Mekanizmaları

Although the precise mechanism of isoniazid (INH) action on Mycobacterium tuberculosis remains poorly understood, the pro-drug INH enters the cytoplasm through simple passive diffusion. It activated by the enzyme catalase/peroxidase encoded by KatG gene. Activation of INH results in the formation o...

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Bibliographic Details
Main Authors: Tanseli Gönlügür, Ugur Gönlügü
Format: Article
Language:English
Published: Dicle University Medical School 2017-09-01
Series:Dicle Medical Journal
Subjects:
Online Access:http://diclemedj.org/upload/sayi/65/Dicle%20Med%20J-03257.PDF