INH Direnç Mekanizmaları
Although the precise mechanism of isoniazid (INH) action on Mycobacterium tuberculosis remains poorly understood, the pro-drug INH enters the cytoplasm through simple passive diffusion. It activated by the enzyme catalase/peroxidase encoded by KatG gene. Activation of INH results in the formation o...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Dicle University Medical School
2017-09-01
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Series: | Dicle Medical Journal |
Subjects: | |
Online Access: | http://diclemedj.org/upload/sayi/65/Dicle%20Med%20J-03257.PDF |