Omics-driven identification and elimination of valerolactam catabolism in Pseudomonas putida KT2440 for increased product titer
Pseudomonas putida is a promising bacterial chassis for metabolic engineering given its ability to metabolize a wide array of carbon sources, especially aromatic compounds derived from lignin. However, this omnivorous metabolism can also be a hindrance when it can naturally metabolize products produ...
Main Authors: | Mitchell G. Thompson, Luis E. Valencia, Jacquelyn M. Blake-Hedges, Pablo Cruz-Morales, Alexandria E. Velasquez, Allison N. Pearson, Lauren N. Sermeno, William A. Sharpless, Veronica T. Benites, Yan Chen, Edward E.K. Baidoo, Christopher J. Petzold, Adam M. Deutschbauer, Jay D. Keasling |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-12-01
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Series: | Metabolic Engineering Communications |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214030119300173 |
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