Omics-driven identification and elimination of valerolactam catabolism in Pseudomonas putida KT2440 for increased product titer

Omics-driven identification and elimination of valerolactam catabolism in Pseudomonas putida KT2440 for increased product titer

Pseudomonas putida is a promising bacterial chassis for metabolic engineering given its ability to metabolize a wide array of carbon sources, especially aromatic compounds derived from lignin. However, this omnivorous metabolism can also be a hindrance when it can naturally metabolize products produ...

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Bibliographic Details
Main Authors: Mitchell G. Thompson, Luis E. Valencia, Jacquelyn M. Blake-Hedges, Pablo Cruz-Morales, Alexandria E. Velasquez, Allison N. Pearson, Lauren N. Sermeno, William A. Sharpless, Veronica T. Benites, Yan Chen, Edward E.K. Baidoo, Christopher J. Petzold, Adam M. Deutschbauer, Jay D. Keasling
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Metabolic Engineering Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030119300173

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http://www.sciencedirect.com/science/article/pii/S2214030119300173

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