Adaptive resistance to immunotherapy directed against p53 can be overcome by global expression of tumor antigens in dendritic cells
Immunotherapy of cancer utilizes dendritic cells (DC) for antigen presentation and the induction of tumor-specific immune responses. However, the therapeutic induction of anti-tumor immunity is limited by tumor escape mechanisms. In this study immortalized dendritic D2SC/1 cells were transduced with...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-10-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00270/full |