Decreased CSF transferrin in sCJD: a potential pre-mortem diagnostic test for prion disorders.

Sporadic Creutzfeldt-Jakob-disease (sCJD) is a fatal neurodegenerative condition that escapes detection until autopsy. Recently, brain iron dyshomeostasis accompanied by increased transferrin (Tf) was reported in sCJD cases. The consequence of this abnormality on cerebrospinal-fluid (CSF) levels of...

Full description

Bibliographic Details
Main Authors: Ajay Singh, Alim J Beveridge, Neena Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3052312?pdf=render