Two discrete events, human T-cell leukemia virus type I Tax oncoprotein expression and a separate stress stimulus, are required for induction of apoptosis in T-cells

<p>Abstract</p> <p>Background</p> <p>It is poorly understood why many transforming proteins reportedly enhance both cell growth (transformation) and cell death (apoptosis). At first glance, the ability to transform and the ability to engender apoptosis seem to be contra...

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Bibliographic Details
Main Authors: Kasai Takefumi, Jeang Kuan-Teh
Format: Article
Language:English
Published: BMC 2004-05-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/1/1/7