EVALUATION OF LINAGLIPTIN DISSOLUTION FROM TABLETS USING HPLC AND UV METHODS

EVALUATION OF LINAGLIPTIN DISSOLUTION FROM TABLETS USING HPLC AND UV METHODS

Linagliptin (LGT) is used to reduce glucose blood levels in patients with type 2 Diabetes mellitus. The proposed conditions for a biowaiver guide can be applied due to high solubility of linagliptin in aqueous media. The aim of the present study was to develop and validate a dissolution test for 5 m...

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Bibliographic Details
Main Authors: Rita Elena de Abreu Engel, Amanda Thomas Barden, Sarah Chagas Campanharo, Natália Olegário, Nadia Maria Volpato, Elfrides Eva Scherman Schapoval
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2019-12-01
Series:Drug Analytical Research
Subjects:
linagliptin
dissolution test
uv spectrophotometric method
hplc method
biowaiver
quality control
Online Access:https://seer.ufrgs.br/dar/article/view/97847/55333

Internet

https://seer.ufrgs.br/dar/article/view/97847/55333

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