Knockdown of estrogen receptor β increases proliferation and affects the transcriptome of endometrial adenocarcinoma cells

Knockdown of estrogen receptor β increases proliferation and affects the transcriptome of endometrial adenocarcinoma cells

Abstract Background Estrogen receptor β (ERβ) has been repeatedly suggested to play important roles in hormone-dependent cancer like in tumors of the breast, ovary or prostate. In this study, we intended to further elucidate its role in endometrial cancer. Methods For this purpose, we knocked down E...

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Bibliographic Details
Main Authors: Oliver Treeck, Elisabeth Diepolder, Maciej Skrzypczak, Susanne Schüler-Toprak, Olaf Ortmann
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Cancer
Subjects:
Estrogen receptor β
siRNA
Endometrial cancer
HEC-1A
RL95/2
Transcriptome analysis
Online Access:http://link.springer.com/article/10.1186/s12885-019-5928-2

Internet

http://link.springer.com/article/10.1186/s12885-019-5928-2

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