Prognostic Enrichment Design in Clinical Trials for Autosomal Dominant Polycystic Kidney Disease: The TEMPO 3:4 Clinical Trial

Prognostic Enrichment Design in Clinical Trials for Autosomal Dominant Polycystic Kidney Disease: The TEMPO 3:4 Clinical Trial

Patients with slowly progressive autosomal dominant polycystic kidney disease (ADPKD) are unlikely to experience outcomes during randomized controlled trials (RCTs). An image classification of ADPKD into typical (diffuse cyst distribution) class 1A to E (by age- and height-adjusted total kidney volu...

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Bibliographic Details
Main Authors: Maria V. Irazabal, Jaime D. Blais, Ronald D. Perrone, Ron T. Gansevoort, Arlene B. Chapman, Olivier Devuyst, Eiji Higashihara, Peter C. Harris, Wen Zhou, John Ouyang, Frank S. Czerwiec, Vicente E. Torres
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Kidney International Reports
Subjects:
autosomal dominant polycystic kidney disease
clinical trials
disease progression
image classification of ADPKD
kidney volume
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024916300511

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http://www.sciencedirect.com/science/article/pii/S2468024916300511

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