Inhibition of Human Immunodeficiency Virus Type 1 Entry by a Keggin Polyoxometalate

Inhibition of Human Immunodeficiency Virus Type 1 Entry by a Keggin Polyoxometalate

Here, we report the anti-human immunodeficiency virus (HIV) potency and underlying mechanisms of a Keggin polyoxometalate (PT-1, K6HPTi2W10O40). Our findings showed that PT-1 exhibited highly potent effects against a diverse group of HIV type 1 (HIV-1) strains and displayed low cytotoxicity and geno...

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Bibliographic Details
Main Authors: Xiaoli Wang, Jiao Wang, Wenmei Zhang, Boye Li, Ying Zhu, Qin Hu, Yishu Yang, Xiaoguang Zhang, Hong Yan, Yi Zeng
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Viruses
Subjects:
human immunodeficiency virus type 1
Keggin polyoxometalate
entry inhibition
CD4
gp41 NHR
Online Access:http://www.mdpi.com/1999-4915/10/5/265

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http://www.mdpi.com/1999-4915/10/5/265

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