KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection.

Following envelope mediated fusion, the HIV-1 core is released into the cytoplasm of the target cell and undergoes a series of trafficking and replicative steps that result in the nuclear import of the viral genome, which ultimately leads to the integration of the proviral DNA into the host cell gen...

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Bibliographic Details
Main Authors: Adarsh Dharan, Sarah Talley, Abhishek Tripathi, João I Mamede, Matthias Majetschak, Thomas J Hope, Edward M Campbell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4915687?pdf=render