Gemtuzumab ozogamicin and novel antibody-drug conjugates in clinical trials for acute myeloid leukemia

Abstract Targeted agents are increasingly used for the therapy of acute myeloid leukemia (AML). Gemtuzumab ozogamicin (GO) is the first antibody-drug conjugate (ADC) approved for induction therapy of AML. When used in fractionated doses, GO combined with the conventional cytarabine/anthracycline-bas...

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Bibliographic Details
Main Authors: Bo Yu, Delong Liu
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Biomarker Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40364-019-0175-x