ERDO - a framework to select an appropriate randomization procedure for clinical trials

ERDO - a framework to select an appropriate randomization procedure for clinical trials

Abstract Background Randomization is considered to be a key feature to protect against bias in randomized clinical trials. Randomization induces comparability with respect to known and unknown covariates, mitigates selection bias, and provides a basis for inference. Although various randomization pr...

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Bibliographic Details
Main Authors: Ralf-Dieter Hilgers, Diane Uschner, William F. Rosenberger, Nicole Heussen
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Medical Research Methodology
Subjects:
Design
Restricted randomization
Selection bias
Chronological bias
Type I error probability
Online Access:http://link.springer.com/article/10.1186/s12874-017-0428-z

Internet

http://link.springer.com/article/10.1186/s12874-017-0428-z

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