Protection of the Geum japonicum Thunb. var. chinense extracts against oxygen-glucose deprivation and re-oxygenation induced astrocytes injury via BDNF/PI3K/Akt/CREB pathway

Geum japonicum Tunb. var. chinense (GJ) is a traditional Chinese medicine usually used for the alleviation of dizziness and headache. Previous studies have reported that the GJ extracts could alleviate cerebral I/R injury by reducing apoptosis in vivo. To further elucidate the positive role and unde...

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Bibliographic Details
Main Authors: Lipeng Du, Zhigang Mei, Yaguang Huang, Wei Tao, Kai Wang, Weifeng Huang, Huajun Zhou, Zhitao Feng
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220303152