Synthesis and Initial Evaluation of a Novel Fluorophore for Selective FMDV 3C Protease Detection

The development and evaluation of a Boc-AL(Boc)Q(Trt)-AMC fluorophore to detect 3C Protease, produced by Foot and Mouth Disease Virus (FMDV) is reported, with a view to a potential use as a rapid screen for FMDV infected livestock The peptide-linked conjugate fluorophore is evaluated in vitro for se...

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Bibliographic Details
Main Authors: Samerah Malik, Alex Sinclair, Ali Ryan, Adam Le Gresley
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/16/3599