Comparative analysis of A-to-I editing in human and non-human primate brains reveals conserved patterns and context-dependent regulation of RNA editing

Comparative analysis of A-to-I editing in human and non-human primate brains reveals conserved patterns and context-dependent regulation of RNA editing

Abstract A-to-I RNA editing is an important process for generating molecular diversity in the brain through modification of transcripts encoding several proteins important for neuronal signaling. We investigated the relationships between the extent of editing at multiple substrate transcripts (5HT2C...

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Bibliographic Details
Main Authors: Richard T. O’Neil, Xiaojing Wang, Michael V. Morabito, Ronald B. Emeson
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Molecular Brain
Subjects:
5HT2C Receptor
Editing Site
Adenosine Deaminase Acting
Editing Efficiency
Discrete Brain Region
Online Access:http://link.springer.com/article/10.1186/s13041-017-0291-1

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http://link.springer.com/article/10.1186/s13041-017-0291-1

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