Higher-order partial least squares for predicting gene expression levels from chromatin states

Abstract Background Extensive studies have shown that gene expression levels are strongly affected by chromatin mark combinations via at least two mechanisms, i.e., activation or repression. But their combinatorial patterns are still unclear. To further understand the relationship between histone mo...

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Bibliographic Details
Main Authors: Shiquan Sun, Xifang Sun, Yan Zheng
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2100-y