4-(1H-Pyrazol-1-yl) Benzenesulfonamide Derivatives: Identifying New Active Antileishmanial Structures for Use against a Neglected Disease

4-(1H-Pyrazol-1-yl) Benzenesulfonamide Derivatives: Identifying New Active Antileishmanial Structures for Use against a Neglected Disease

Leishmaniasis is a neglected disease responsible for about 56,000 deaths every year. Despite its importance, there are no effective, safe and proper treatments for leishmaniasis due to strain resistance and/or drug side-effects. In this work we report the synthesis, molecular modeling, cytotoxicity...

Full description

Bibliographic Details
Main Authors: Leonor L. Leon, Veronica F. Amaral, Marilene M. Canto-Cavalheiro, Carlos R. Rodrigues, Júlio C. Borges, Alessandra M. T. Souza, Cesar D. Oliveira, Helena C. Castro, Marie-Luce F. Lira, Tathiane A. Proux, Karen S. Charret, Alice M. R. Bernardino, Roberta K. F. Marra
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Molecules
Subjects:
pyrazoles
benzenesulfonamide
Leishmania
cytotoxicity
in silico evaluation
Online Access:http://www.mdpi.com/1420-3049/17/11/12961

Internet

http://www.mdpi.com/1420-3049/17/11/12961

Similar Items