Performance of protein-ligand docking with CDK4/6 inhibitors: a case study

Performance of protein-ligand docking with CDK4/6 inhibitors: a case study

It is widely believed that tertiary protein-ligand interactions are essential in determining protein function. Currently, the structure sampling and scoring function in traditional docking methods still have limitations. Therefore, new methods for protein-ligand docking are desirable. The accurate d...

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Bibliographic Details
Main Authors: Linlu Song, Shangbo Ning, Jinxuan Hou, Yunjie Zhao
Format: Article
Language:English
Published: AIMS Press 2021-04-01
Series:Mathematical Biosciences and Engineering
Subjects:
protein-ligand docking
multi-source information
cdk4/6 inhibitor
structure sampling
scoring function
breast cancer
Online Access:http://www.aimspress.com/article/doi/10.3934/mbe.2021025?viewType=HTML

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http://www.aimspress.com/article/doi/10.3934/mbe.2021025?viewType=HTML

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