High Variability in Cellular Proliferation, Gene Expression, and Cytokine Production in the Nonneoplastic Colonic Epithelium of Young Apc+/Min-FCCC Mice

High Variability in Cellular Proliferation, Gene Expression, and Cytokine Production in the Nonneoplastic Colonic Epithelium of Young Apc+/Min-FCCC Mice

An urgent need exists to identify efficacious therapeutic preventive interventions for individuals who are at high risk of developing colorectal cancer. To maximize the benefits of preventive intervention, it is vital to identify the time interval during which the initiation of a preventive interven...

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Bibliographic Details
Main Authors: Alyssa A. Leystra, Kristen N. Harvey, Esther Kaunga, Harvey Hensley, Lisa A. Vanderveer, Karthik Devarajan, Margie L. Clapper
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer prevention
cancer prevention
cytokine signaling
tumor initiation
chemoprevention
immunoprevention
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.705562/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.705562/full

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