Staphylococcal SSL5 Binding to Human Leukemia Cells Inhibits Cell Adhesion to Endothelial Cells and Platelets

Bacterial proteins provide promising tools for novel anticancer therapies. Staphylococcal superantigen-like 5 (SSL5) was recently described to bind P-selectin glycoprotein ligand-1 (PSGL-1) on leukocytes and to inhibit neutrophil rolling on a P-selectin surface. As leukocytes and tumor cells share m...

Full description

Bibliographic Details
Main Authors: Annemiek M. E. Walenkamp, Jovanka Bestebroer, Ingrid G. J. Boer, Roeline Kruizinga, Henk M. Verheul, Jos A. G. van Strijp, Carla J. C. de Haas
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2009-0486