Interaction of anthelmintic drug (thiabendazole) with DNA: Spectroscopic and molecular modeling studies
The interaction between thiabendazole (TBZ) and calf-thymus DNA (ct-DNA) was studied by experimental and molecular modeling methods. The intrinsic fluorescence of TBZ was quenched in the presence of ct-DNA. In competition experiments, TBZ could displace Hoechst 33258 (a minor groove binder to DNA),...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-05-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535214001117 |