Activation of a Specific Gut Bacteroides-Folate-Liver Axis Benefits for the Alleviation of Nonalcoholic Hepatic Steatosis

Activation of a Specific Gut Bacteroides-Folate-Liver Axis Benefits for the Alleviation of Nonalcoholic Hepatic Steatosis

Summary: A beneficial gut Bacteroides-folate-liver pathway regulating lipid metabolism is demonstrated. Oral administration of a Ganoderma meroterpene derivative (GMD) ameliorates nonalcoholic hepatic steatosis in the liver of fa/fa rats by reducing endotoxemia, enhancing lipid oxidation, decreasing...

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Bibliographic Details
Main Authors: Shanshan Qiao, Li Bao, Kai Wang, Shanshan Sun, Mingfang Liao, Chang Liu, Nan Zhou, Ke Ma, Yuwei Zhang, Yihua Chen, Shuang-Jiang Liu, Hongwei Liu
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Cell Reports
Subjects:
nonalcoholic hepatic steatosis
a Ganoderma meroterpene derivative
a gut Bacteroides-folate-liver axis
Bacteroides xylanisolvens
Bacteroides
folate
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720309906

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http://www.sciencedirect.com/science/article/pii/S2211124720309906

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