Age-Dependent Dysregulation of Muscle Vasculature and Blood Flow Recovery after Hindlimb Ischemia in the <i>mdx</i> Model of Duchenne Muscular Dystrophy

Age-Dependent Dysregulation of Muscle Vasculature and Blood Flow Recovery after Hindlimb Ischemia in the <i>mdx</i> Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD), caused by a lack of functional dystrophin, is characterized by progressive muscle degeneration. Interestingly, dystrophin is also expressed in endothelial cells (ECs), and insufficient angiogenesis has already been hypothesized to contribute to DMD pathology, howev...

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Bibliographic Details
Main Authors: Paulina Podkalicka, Olga Mucha, Katarzyna Kaziród, Iwona Bronisz-Budzyńska, Sophie Ostrowska-Paton, Mateusz Tomczyk, Kalina Andrysiak, Jacek Stępniewski, Józef Dulak, Agnieszka Łoboda
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
DMD
Duchenne muscular dystrophy
angiogenesis
endothelial cells
hindlimb ischemia
retinal angiogenesis
Online Access:https://www.mdpi.com/2227-9059/9/5/481

Internet

https://www.mdpi.com/2227-9059/9/5/481

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