Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway.

Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway.

Hepatic progenitor cells (HPCs) appear to play an important role in chronic liver injury. In this study, cirrhosis was induced in F-344 rats (n = 32) via subcutaneous injection of 50% carbon tetrachloride (CCl4) twice a week for 8 weeks. Then, 30% CCl4 was administered in conjunction with intragastr...

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Bibliographic Details
Main Authors: Jiamei Chen, Xiao Zhang, Ying Xu, Xuewei Li, Shuang Ren, Yaning Zhou, Yuyou Duan, Mark Zern, Hua Zhang, Gaofeng Chen, Chenghai Liu, Yongping Mu, Ping Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4473299?pdf=render

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http://europepmc.org/articles/PMC4473299?pdf=render

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