Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus
<p>Abstract</p> <p>Background</p> <p>HIV-1 infects non-dividing cells. This implies that the virus traverses the nuclear pore before it integrates into chromosomal DNA. Recent studies demonstrated that TNPO3 is required for full infectivity of HIV-1. The fact that TNPO3...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-12-01
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Series: | Retrovirology |
Subjects: | |
Online Access: | http://www.retrovirology.com/content/8/1/98 |