Towards physiologically relevant human pluripotent stem cell (hPSC) models of Parkinson’s disease

Abstract The derivation of human embryonic stem cells followed by the discovery of induced pluripotent stem cells and leaps in genome editing approaches have continuously fueled enthusiasm for the development of new models of neurodegenerative diseases such as Parkinson’s disease (PD). PD is charact...

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Bibliographic Details
Main Authors: Elena Coccia, Tim Ahfeldt
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Stem Cell Research & Therapy
Subjects:
GBA
Online Access:https://doi.org/10.1186/s13287-021-02326-5