In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse

In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse

Methylation of cytosines (5meC) is a widespread heritable DNA modification. During mammalian development, two global demethylation events are followed by waves of de novo DNA methylation. In vivo mechanisms of DNA methylation establishment are largely uncharacterized. Here, we use Saccharomyces cere...

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Bibliographic Details
Main Authors: Marco Morselli, William A Pastor, Barbara Montanini, Kevin Nee, Roberto Ferrari, Kai Fu, Giancarlo Bonora, Liudmilla Rubbi, Amander T Clark, Simone Ottonello, Steven E Jacobsen, Matteo Pellegrini
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
DNMT3
histone
H3K36me3
H3K4me3
DNA methylation
Online Access:https://elifesciences.org/articles/06205

Internet

https://elifesciences.org/articles/06205

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