HCV Core Protein Induces Chemokine CCL2 and CXCL10 Expression Through NF-κB Signaling Pathway in Macrophages

HCV Core Protein Induces Chemokine CCL2 and CXCL10 Expression Through NF-κB Signaling Pathway in Macrophages

HCV core protein is the first structural protein synthesized during hepatitis C virus (HCV) infection and replication. It is released from virus infected liver cells and mediates multiple functions to affect host cell response. The innate immune response is the first line of defense against viral in...

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Bibliographic Details
Main Authors: Xiaotian Song, Xue Gao, Yadong Wang, Rameez Raja, Yaoyu Zhang, Shulin Yang, Miao Li, Zhiyan Yao, Lin Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
HCV core protein
macrophages
chemokines
CCL2
CXCL10
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.654998/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.654998/full

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