Biological and clinical implications of cancer stem cells in primary brain tumors

Despite therapeutic advances, glioblastoma multiforme (GBM) remains a lethal disease. The infiltrative nature of this disease and the presence of a cellular population resistant to current medical treatments account for the poor prognosis of these patients. Growing evidence indicates the existence o...

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Bibliographic Details
Main Authors: Marcello eMaugeri-Saccà, Simona edi Martino, Ruggero eDe Maria
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00006/full