Increase of circulating memory B cells after glucocorticoid-induced remission identifies patients at risk of IgG4-related disease relapse

Increase of circulating memory B cells after glucocorticoid-induced remission identifies patients at risk of IgG4-related disease relapse

Abstract Background Immunoglobulin G4-related disease (IgG4-RD) promptly responds to glucocorticoids but relapses in a considerable fraction of patients. Reliable biomarkers of flare are currently lacking because the pathophysiology of IgG4-RD remains largely elusive. In the present work, we aimed t...

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Bibliographic Details
Main Authors: Marco Lanzillotta, Emanuel Della-Torre, Raffaella Milani, Enrica Bozzolo, Emanuele Bozzalla-Cassione, Lucrezia Rovati, Paolo Giorgio Arcidiacono, Stefano Partelli, Massimo Falconi, Fabio Ciceri, Lorenzo Dagna
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Arthritis Research & Therapy
Subjects:
IgG4
IgG4-related disease
B cells
Plasmablasts
Corticosteroid
Glucocorticoid
Online Access:http://link.springer.com/article/10.1186/s13075-018-1718-5

Internet

http://link.springer.com/article/10.1186/s13075-018-1718-5

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