Structural changes in the cytoplasmic pore of the Kir1.1 channel during pH<sub>i</sub>-gating probed by FRET

<p>Abstract</p> <p>Kir1.1 channels are important in maintaining K<sup>+ </sup>homeostasis in the kidney. Intracellular acidification reversibly closes the Kir1.1 channel and thus decreases K<sup>+ </sup>secretion. In this study, we used Foster resonance ener...

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Bibliographic Details
Main Authors: Shieh Ru-Chi, Lee Jay-Ron
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/29