MiR-200c-3p Modulates Cisplatin Resistance in Biliary Tract Cancer by ZEB1-Independent Mechanisms

MiR-200c-3p Modulates Cisplatin Resistance in Biliary Tract Cancer by ZEB1-Independent Mechanisms

Biliary tract cancer is a major global health issue in cancer-related mortality. Therapeutic options are limited, and cisplatin-based treatment schedules represent the mainstay of first-line therapeutic strategies. Although the gain of survival by the addition of cisplatin to gemcitabine is moderate...

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Bibliographic Details
Main Authors: Florian Posch, Felix Prinz, Amar Balihodzic, Christian Mayr, Tobias Kiesslich, Christiane Klec, Katharina Jonas, Dominik A. Barth, Jakob M. Riedl, Armin Gerger, Martin Pichler
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
biliary tract cancer
chemoresistance
cisplatin resistance
epithelial–mesenchymal transition
miR-200c-3p
ZEB1
Online Access:https://www.mdpi.com/2072-6694/13/16/3996

Internet

https://www.mdpi.com/2072-6694/13/16/3996

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