Cancer of unknown primary with EGFR mutation successfully treated with targeted therapy directed by clinical next-generation sequencing: a case report

Abstract Background Cancer of unknown primary (CUP) is usually treated with nonselective and empirical chemotherapy; however, its prognosis is generally poor, with a median survival of less than a year. Thus, clinicians eagerly await the development of more effective treatment strategies. In recent...

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Bibliographic Details
Main Authors: Yosuke Mitani, Masashi Kanai, Tadayuki Kou, Shigeki Kataoka, Keitaro Doi, Junichi Matsubara, Shinya Ohashi, Shigemi Matsumoto, Manabu Muto
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-020-07640-4