Fractioned Dose Regimen of Sunitinib for Patients with Gastrointestinal Stromal Tumor: A Pharmacokinetic and Treatment Efficacy Study

AIM: Sunitinib has shown benefit in patients with imatinib (IM)–resistant gastrointestinal stromal tumor (GIST). However, its advantages are somewhat diminished because of associated toxicities. Herein, we clarify the efficacy and safety of fractioned dose regimen of sunitinib by a pharmacokinetic a...

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Bibliographic Details
Main Authors: Yen-Yang Chen, Chun-Nan Yeh, Chi-Tung Cheng, Chao-En Wu, Kun-Chun Chiang, Tsung-Wen Chen, Chih-Chi Wang, Jen-Shi Chen, Ta-Sen Yeh
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652331400093X