Novel protective and risk loci in hip dysplasia in German Shepherds.

Canine hip dysplasia is a common, non-congenital, complex and hereditary disorder. It can inflict severe pain via secondary osteoarthritis and lead to euthanasia. An analogous disorder exists in humans. The genetic background of hip dysplasia in both species has remained ambiguous despite rigorous s...

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Bibliographic Details
Main Authors: Lea I Mikkola, Saila Holopainen, Anu K Lappalainen, Tiina Pessa-Morikawa, Thomas J P Augustine, Meharji Arumilli, Marjo K Hytönen, Osmo Hakosalo, Hannes Lohi, Antti Iivanainen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008197