PROTS-RF: a robust model for predicting mutation-induced protein stability changes.

The ability to improve protein thermostability via protein engineering is of great scientific interest and also has significant practical value. In this report we present PROTS-RF, a robust model based on the Random Forest algorithm capable of predicting thermostability changes induced by not only s...

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Bibliographic Details
Main Authors: Yunqi Li, Jianwen Fang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471942?pdf=render