Glycosaminoglycans as Tools to Decipher the Platelet Tumor Cell Interaction: A Focus on P-Selectin

Glycosaminoglycans as Tools to Decipher the Platelet Tumor Cell Interaction: A Focus on P-Selectin

Tumor cell−platelet interactions are regarded as an initial crucial step in hematogenous metastasis. Platelets protect tumor cells from immune surveillance in the blood, mediate vascular arrest, facilitate tumor extravasation, growth, and finally angiogenesis in the metastatic foci. Tumor...

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Bibliographic Details
Main Authors: Svenja Schwarz, Lukas Maria Gockel, Annamaria Naggi, Uri Barash, Martina Gobec, Gerd Bendas, Martin Schlesinger
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
ro-heparin
2-<i>o</i>-desulfated heparin
hexasaccharide heparin fragment
decasaccharide heparin fragment
unfractionated heparin
low molecular weight heparin
platelets
p-selectin
platelet aggregation
platelet secretion
tumor metastasis
Online Access:https://www.mdpi.com/1420-3049/25/5/1039

Internet

https://www.mdpi.com/1420-3049/25/5/1039

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