MyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infection.

MyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infection.

Type I interferons (IFNs) are cytokines that orchestrate diverse immune responses to viral and bacterial infections. Although typically considered to be most important molecules in response to viruses, type I IFNs are also induced by most, if not all, bacterial pathogens. In this study, we addressed...

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Bibliographic Details
Main Authors: Leonardo A de Almeida, Natalia B Carvalho, Fernanda S Oliveira, Thais L S Lacerda, Anilton C Vasconcelos, Lucas Nogueira, Andre Bafica, Aristóbolo M Silva, Sergio C Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3149075?pdf=render

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http://europepmc.org/articles/PMC3149075?pdf=render

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