An improved bind-n-seq strategy to determine protein-DNA interactions validated using the bacterial transcriptional regulator YipR

Abstract Background Interactions between transcription factors and DNA lie at the centre of many biological processes including DNA recombination, replication, repair and transcription. Most bacteria encode diverse proteins that act as transcription factors to regulate various traits. Several techno...

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Bibliographic Details
Main Authors: Shi-qi An, Miguel A. Valvano, Yan-hua Yu, Jeremy S. Webb, Guillermo Lopez Campos
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-019-1672-7