Ginsenoside-Rb1-Mediated Anti-angiogenesis via Regulating PEDF and miR-33a through the Activation of PPAR-γ Pathway

Ginsenoside-Rb1-Mediated Anti-angiogenesis via Regulating PEDF and miR-33a through the Activation of PPAR-γ Pathway

Angiogenesis is the formation of new blood vessels from the existing vasculature, which is involved in multiple biological processes, including atherosclerosis, ischemic heart disease, and cancer. Ginsenoside-Rb1 (Rb1), the most abundant ginsenoside isolated form Panax ginseng, has been identified a...

Full description

Bibliographic Details
Main Authors: Huixia Lu, Xunian Zhou, Hoi-Hin Kwok, Mei Dong, Zhaoqiang Liu, Po-Ying Poon, Xiaorong Luan, Ricky Ngok-Shun Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Pharmacology
Subjects:
ginsenoside Rb1
angiogenesis
miR-33a
PEDF
peroxisome proliferator-activated receptor-γ (PPAR-γ)
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00783/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00783/full

Similar Items