A Novel Small Molecule, LCG-N25, Inhibits Oral Streptococcal Biofilm

A Novel Small Molecule, LCG-N25, Inhibits Oral Streptococcal Biofilm

Dental caries is a chronic oral infectious disease caused by cariogenic biofilm adhered on the tooth surface. Our previous study demonstrated that a repurposed natural compound napabucasin (NAP) showed good antimicrobial activity against oral streptococcal biofilms. The current study designed a nove...

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Bibliographic Details
Main Authors: Xiaoying Lyu, Chungen Li, Jin Zhang, Liang Wang, Qingsong Jiang, Yusen Shui, Lan Chen, Youfu Luo, Xin Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Microbiology
Subjects:
dental caries
oral biofilm
Streptococcus mutans
antimicrobial small molecule
cytotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.654692/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.654692/full

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