Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential
Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) promote the survival of midbrain dopaminergic neurons which degenerate in Parkinson's disease (PD). However, CDNF and MANF are structurally and functionally clearly distinct from the clas...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-01-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996116301711 |