Fibroblast growth factor 21 inhibits atherosclerosis in apoE−/− mice by ameliorating Fas-mediated apoptosis

Fibroblast growth factor 21 inhibits atherosclerosis in apoE−/− mice by ameliorating Fas-mediated apoptosis

Abstract Background FGF21 is a critical endogenous regulator in energy homeostasis and systemic glucose and lipid metabolism. Despite intensive study of the metabolic functions of FGF21, its important role in heart disease needs further exploration. Apoptosis induced by ox-LDL in vascular endothelia...

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Bibliographic Details
Main Authors: Xinxin Yan, Zhongshan Gou, Yuan Li, Yu Wang, Jingyan Zhu, Guidong Xu, Qian Zhang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Lipids in Health and Disease
Subjects:
Fibroblast growth factor 21
Fas
Apoptosis
Atherosclerosis
Online Access:http://link.springer.com/article/10.1186/s12944-018-0846-x

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http://link.springer.com/article/10.1186/s12944-018-0846-x

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