Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis

Diosgenin Glucoside Protects against Spinal Cord Injury by Regulating Autophagy and Alleviating Apoptosis

Spinal cord injury (SCI) is a severe traumatic lesion of central nervous system (CNS) with only a limited number of restorative therapeutic options. Diosgenin glucoside (DG), a major bioactive ingredient of Trillium tschonoskii Max., possesses neuroprotective effects through its antioxidant and anti...

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Bibliographic Details
Main Authors: Xian-Bing Chen, Zi-Li Wang, Qing-Yu Yang, Fang-Yu Zhao, Xiao-Li Qin, Xian-E Tang, Jun-Long Du, Zong-Hai Chen, Kui Zhang, Fei-Jun Huang
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
spinal cord injury
autophagy
diosgenin glucoside
Rheb/mTOR signal pathway
miR-155-3p
apoptosis
Online Access:http://www.mdpi.com/1422-0067/19/8/2274

Internet

http://www.mdpi.com/1422-0067/19/8/2274

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