Green, lithium salt-free synthesis of 2-alkylated 1,4-benzenediols in hydroalcoholic media

Herein, we describe an efficient, green, and lithium salt-free synthesis of 2-substituted 1,4-benzenediol in water/ethanol as solvent and potassium carbonate as a base. Optimized reaction time, the required equivalent of base and the observed solvent effect are reported.

Bibliographic Details
Main Authors: Alejandro Peixoto de Abreu Lima, Natali Graziano, Enrique Pandolfi
Format: Article
Language:English
Published: Taylor & Francis Group 2016-10-01
Series:Green Chemistry Letters and Reviews
Subjects:
Online Access:http://dx.doi.org/10.1080/17518253.2016.1238966