Toxoplasma gondii inhibits cytochrome c-induced caspase activation in its host cell by interference with holo-apoptosome assembly
Inhibition of programmed cell death pathways of mammalian cells often facilitates the sustained survival of intracellular microorganisms. The apicomplexan parasite Toxoplasma gondii is a master regulator of host cell apoptotic pathways. Here, we have characterized a novel anti-apoptotic acti...
Main Authors: | Kristin Graumann, Frieder Schaumburg, Thomas F. Reubold, Diana Hippe, Susanne Eschenburg, Carsten G. K. Lüder |
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Format: | Article |
Language: | English |
Published: |
Shared Science Publishers OG
2015-05-01
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Series: | Microbial Cell |
Subjects: | |
Online Access: | http://microbialcell.com/researcharticles/toxoplasma-gondii-inhibits-cytochrome-c-induced-caspase-activation-in-its-host-cell-by-interference-with-holo-apoptosome-assembly/ |
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