Beyond Parkinson disease: amyotrophic lateral sclerosis and the axon guidance pathway.

We recently described a genomic pathway approach to study complex diseases. We demonstrated that models constructed using single nucleotide polymorphisms (SNPs) within axon guidance pathway genes were highly predictive of Parkinson disease (PD) susceptibility, survival free of PD, and age at onset o...

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Bibliographic Details
Main Authors: Timothy G Lesnick, Eric J Sorenson, J Eric Ahlskog, John R Henley, Lina Shehadeh, Spiridon Papapetropoulos, Demetrius M Maraganore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2175528?pdf=render